The city of Sanibel is located on Sanibel Island in Lee County, Florida. Sanibel is what is referred to as a barrier island - a sandy collection on Pine Island's leeward side - which is more solid coral-rock. The entire island is incorporated by the city of Sanibel, with a majority of the city property located on the island's east end. The United States Census Bureau reports that the total area of the city is 33.16 square miles.

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